Hi Martin!
Yes, CH340 was the first I try to install after your advice. And finally it work after install the driver and I have test programming to ESP32 and it work

I though that everything would work after install the ESP32 chain tool, but what a fight

so I am glad for your support and help, that guided me in right direction, and maybe this could help other too.
But unfortunately, I still have the problem with GPS macro. I think there is an issue with this component. I have now updated my pc in my workshop too and now the GPS is not working with Arduino also
I have tested with 3 different GPS device. I have measured with an Ocilloscope, the data out of the GPS look fine.
To be sure the Uart work, I perform a test with 2 RF module (HC12) and it work perfect communication work fine, data in and out. So my conclution is there is someting wrong with GPS component in ESP32 and for the Arduino, aerlier it work with Arduino?
Do you have a GPS to make a test with?
Loong story.
Br jorgen